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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
10.3
Human Site:
Y325
Identified Species:
16.19
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
Y325
S
P
T
P
A
D
D
Y
N
F
N
L
D
D
N
Chimpanzee
Pan troglodytes
XP_511025
426
45548
P310
L
S
S
L
P
L
G
P
T
T
L
D
T
W
P
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
Y325
S
P
T
P
A
D
D
Y
N
F
N
L
D
D
N
Dog
Lupus familis
XP_853833
304
33793
L287
A
D
D
Y
N
F
N
L
D
D
N
E
G
V
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
N315
P
T
P
A
D
D
Y
N
F
N
L
D
D
N
E
Rat
Rattus norvegicus
Q62814
300
33206
N286
Y
N
F
N
L
D
D
N
E
G
V
C
D
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
D212
D
Y
N
F
N
L
D
D
N
E
G
V
C
D
L
Chicken
Gallus gallus
Q90977
403
43534
G384
Y
H
F
G
L
E
E
G
E
G
I
S
E
L
F
Frog
Xenopus laevis
NP_001086706
375
40890
S287
S
S
A
S
L
D
N
S
N
D
S
P
D
P
S
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
A287
T
S
T
P
D
T
T
A
N
P
T
P
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
Y643
S
Q
P
P
T
I
G
Y
G
S
S
Q
R
R
S
Honey Bee
Apis mellifera
XP_624285
300
34327
S286
K
D
Y
H
F
N
L
S
E
N
E
G
I
C
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
D335
S
P
A
P
N
D
Q
D
Y
Y
F
N
L
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
T406
S
M
T
N
M
W
E
T
G
P
D
E
W
D
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
I442
W
L
L
S
N
A
E
I
S
M
T
D
I
W
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
0
100
6.6
N.A.
13.3
20
N.A.
20
0
26.6
20
N.A.
20
0
N.A.
33.3
P-Site Similarity:
100
6.6
100
26.6
N.A.
20
20
N.A.
26.6
20
46.6
33.3
N.A.
33.3
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
7
14
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
7
% C
% Asp:
7
14
7
0
14
40
27
14
7
14
7
20
34
34
20
% D
% Glu:
0
0
0
0
0
7
20
0
20
7
7
14
7
0
7
% E
% Phe:
0
0
14
7
7
7
0
0
7
14
7
0
0
0
14
% F
% Gly:
0
0
0
7
0
0
14
7
14
14
7
7
7
0
7
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
7
0
0
7
0
14
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
7
7
7
7
20
14
7
7
0
0
14
14
7
14
7
% L
% Met:
0
7
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
7
14
27
7
14
14
34
14
20
7
0
7
14
% N
% Pro:
7
20
14
34
7
0
0
7
0
14
0
14
0
7
7
% P
% Gln:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% R
% Ser:
40
20
7
14
0
0
0
14
7
7
14
7
7
0
14
% S
% Thr:
7
7
27
0
7
7
7
7
7
7
14
0
7
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
7
0
7
0
% V
% Trp:
7
0
0
0
0
7
0
0
0
0
0
0
7
14
0
% W
% Tyr:
14
7
7
7
0
0
7
20
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _